1-(2-Fluoro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-fluorophenol - Names and Identifiers
1-(2-Fluoro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-fluorophenol - Physico-chemical Properties
Molecular Formula | C8H7FO2
|
Molar Mass | 154.14 |
Density | 1.1850 (estimate) |
Melting Point | 120-124 °C |
Boling Point | 203.5°C (rough estimate) |
Flash Point | 130.8°C |
Water Solubility | insoluble |
Vapor Presure | 0.00103mmHg at 25°C |
BRN | 696642 |
pKa | 7.17±0.18(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.529 |
MDL | MFCD00142713 |
1-(2-Fluoro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-fluorophenol - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
R52 - Harmful to aquatic organisms
|
Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S24/25 - Avoid contact with skin and eyes.
|
HS Code | 29143990 |
Hazard Class | IRRITANT |
1-(2-Fluoro-4-hydroxyphenyl)ethan-1-one, 4-Acetyl-3-fluorophenol - Introduction
It is an organic compound with the chemical formula C8H7FO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a white crystalline solid.
-Melting point: About 79-81 ° C.
-Boiling point: About 237-239 ° C.
-Solubility: Soluble in ethanol, chloroform and ether and other organic solvents.
Use:
-is often used as an important intermediate in organic synthesis. It can be used to prepare a series of other organic compounds, such as drugs, dyes and pesticides.
-It can also be used as a precursor of organometallic ligands, and can be used in catalytic reactions and coordination chemistry.
Method:
The commonly used methods of preparation are as follows:
1. Reaction of acetophenone with hydrogen fluoride to give 2-fluoro-acetophenone.
2. Then, under alkaline conditions, 2-fluoro-acetophenone is reacted with sodium hydroxide to obtain Fluorene.
Safety Information:
-The toxicity information is very limited, so care should be taken when using or handling it.
-During operation, appropriate protective measures need to be taken, including wearing protective glasses, gloves and laboratory coats.
-When in contact with skin, eyes or body, rinse immediately with plenty of water and seek medical assistance.
-When storing, store it in a dry and sealed container, away from fire and oxidizing agents.
-When disposing of waste from this compound, comply with local regulations and ensure safe disposal.
Last Update:2024-04-09 20:49:11